C6292

Sigma

 

Monoclonal Anti-Caldesmon antibody produced in mouse

clone CALD-8, ascites fluid

MDL number:MFCD00164554

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Description

Immunogencaldesmon from turkey gizzard
SpecificityThe antibody localizes the high molecular weight form of caldesmon in chicken or turkey gizzard and the low molecular weight form of caldesmon in chicken fibroblasts by immunoblotting. The antibody detects epitopes located on the non-calmodulin-binding part of caldesmon, more specifically, the central region of the molecule.

Properties

antibody formascites fluid
cloneCALD-8 (monoclonal)
contains15 mM sodium azide
species reactivityhuman, pig, rabbit, guinea pig
application(s)immunoblotting: 1:400 using pig stomach caldesmon extract
 indirect immunofluorescence: suitable using frozen human tissue sections
isotypeIgG1
Gene Informationhuman ... CALD1(800)
shipped indry ice
storage temp.−20°C

Safety

WGK GermanyNWG

References

referenceDurard-Arczyrska, W., et al. Histochemistry 100, 465, (1993) Abstract
 Salisbury, J.L., et al., A transformation-associated complex involving tyrosine kinase signal adapter proteins and caldesmon links v-erbB signaling to actin stress fiber disassembly. Proc. Natl. Acad. Sci. U. S. A. 94, 11351-11356, (1997) Abstract