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C6292
Sigma
Monoclonal Anti-Caldesmon antibody produced in mouse
clone CALD-8, ascites fluid
| MDL number: | MFCD00164554 |
Description
| Immunogen | caldesmon from turkey gizzard |
| Specificity | The antibody localizes the high molecular weight form of caldesmon in chicken or turkey gizzard and the low molecular weight form of caldesmon in chicken fibroblasts by immunoblotting. The antibody detects epitopes located on the non-calmodulin-binding part of caldesmon, more specifically, the central region of the molecule. |
Properties
| antibody form | ascites fluid |
| clone | CALD-8 (monoclonal) |
| contains | 15 mM sodium azide |
| species reactivity | human, pig, rabbit, guinea pig |
| application(s) | immunoblotting: 1:400 using pig stomach caldesmon extract |
| indirect immunofluorescence: suitable using frozen human tissue sections | |
| isotype | IgG1 |
| Gene Information | human ... CALD1(800) |
| shipped in | dry ice |
| storage temp. | −20°C |
Safety
| WGK Germany | NWG |
References
| reference | Durard-Arczyrska, W., et al. Histochemistry 100, 465, (1993) Abstract |
| Salisbury, J.L., et al., A transformation-associated complex involving tyrosine kinase signal adapter proteins and caldesmon links v-erbB signaling to actin stress fiber disassembly. Proc. Natl. Acad. Sci. U. S. A. 94, 11351-11356, (1997) Abstract |




